SMA Types and Differences: Progression and Treatment
Spinal Muscular Atrophy (SMA) is a genetic disorder that affects motor nerve cells. This disorder causes muscle weakness and loss, significantly affecting a person's movement abilities. There are several SMA types, and each is characterized by different symptoms, levels of severity, and prognoses.
Types of SMA
Type 1: Werdnig-Hoffmann Disease
This type usually appears in infancy. Babies experience poor muscle tone, weakness, and a significant loss of movement abilities. Type 1 is the most severe form of SMA and usually shows symptoms in the first 6 months of life.
Type 2: Intermediate SMA
Intermediate SMA usually occurs between 6 and 18 months. In this type, children can sit up on their own but have limited ability to walk. Type 2 has a milder course and a longer lifesp...